Tag Archives: Pfizer Lipitor

How the Dow's Pharma Stocks Have Fared in 2013

By Dan Caplinger, The Motley Fool

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The Dow Jones Industrial Average isn’t just for industrial stocks anymore. You can find all sorts of companies in the venerable average, with the Dow representing a nearly all-inclusive cross-section of the entire U.S. economy.

Pharma stocks aren’t a huge part of the Dow, with just two of its constituents focused solely on the space and a third reaping a substantial portion of its revenue from pharmaceuticals. Yet pharma stocks have made a big impression on investors because of their lucrative dividend yields. Let’s take a look at how these companies have fared so far in 2013 and what their prospects are for the rest of the year and beyond.

JNJ Total Return Price data by YCharts.

You may not think of Johnson & Johnson as a pharmaceutical company, as it’s far better-known for its consumer products. But the health care conglomerate also produces proprietary drugs and medical devices, giving it a broad reach over the entire health care industry. Lately, even as the company has faced liability from recalls of its artificial hip replacements, Johnson & Johnson has gotten help from its pharma division, as the approval of its type 2 diabetes drug Invokana represents a big step forward in diabetes treatment that could produce the company’s next blockbuster.

Meanwhile, pure pharma stocks Pfizer and Merck have both dealt with patent expirations of high-profile drugs over the past couple of years, including Merck’s Singulair and Pfizer’s Lipitor. Yet while revenue has predictably fallen since generic competition hit the market, both companies have held up better than pessimists had expected.

For Pfizer, anticlotting drug Eliquis, which it co-developed with Bristol-Myers Squibb, has the potential to generate billions in sales over the next decade, having several advantages over rival drugs designed to replace the existing warfarin treatment for atrial fibrillation. Merck still faces some patent-cliff problems, with Vytorin, Nasonex, and Zetia coming off patent over the next four years. But with the combination of existing diabetes drugs Januvia and Janumet and up-and-coming development-stage drugs like insomnia treatment suvorexant and osteoporosis drug odanacatib, Merck has good prospects looking forward.

Keep looking for healthy results
With the pharma industry having turned the patent-cliff corner, pharma stocks should continue contributing to the Dow’s overall success. Given the emphasis on dividend income, the big yields that Pfizer and Merck pay will likely remain big drawing points for years to come.

As big as Johnson & Johnson is in health care, some critics are convinced that the company is spread too thin. Is Johnson & Johnson overextended, or is it a well-diversified health-care giant that deserves a place in your portfolio? Find out our view by checking out the Fool’s new premium report. Inside, our analyst outlines the Johnson & Johnson story in terms that any investor can understand. Claim your copy by clicking here now

Source: FULL ARTICLE at DailyFinance

Disney May Help End Dow's Record Run

By Travis Hoium, The Motley Fool

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It’s a quiet day on the economic front, giving investors little reason to move markets sharply higher or lower. As of 3:20 p.m. EDT, the Dow Jones Industrial Average is up a minuscule 0.02%, while the S&P 500 is down just 0.21%. On a company level, the fireworks are a bit brighter. Ten of the Dow’s 30 components have moved more than 1% today; here are the highlights.

Disney has dropped 1% today after the company announced a change in strategy for Lucasfilm’s Star Wars TV series. Star Wars: The Clone Wars will no longer make new episodes for Cartoon Network, but beyond that, details are sparse. The company will produce some sort of Star Wars content “set in a time period previously untouched” but didn’t say when or where the content would appear. Conventional wisdom would say Disney XD has a shot, and we’ll have to wait and see if that’s the case.

Caterpillar is the Dow’s biggest loser with a 1.7% drop today. Industrials are trading lower today, although there’s little news driving the move south. The stock is one of the few Dow components that hasn’t participated in the 2013 rally, essentially trading flat for the year. A disappointing fourth quarter and worry over economic growth both in China and at home have held the stock back recently.

Merck is among the stocks bucking the negative trend in a big way, climbing 3.1% today. The company got the OK to continue a large trial of Vytorin, a cholesterol drug that would compete with Pfizer’s Lipitor. Final results won’t be in until late next year, but with a huge market potential, this is a big step forward for the drug.

Sizing up Disney?
It’s easy to forget that Walt Disney is more than just the House of Mouse. True, Disney amusement parks around the world hosted more than 121 million guests in 2011. But from its vast catalog of characters to its monster collection of media networks, much of Disney’s allure for investors lies in its diversity, and The Motley Fool’s new premium research report lays out the case for investing in Disney today. This report includes the key items investors must watch, as well as the opportunities and threats the company faces going forward. So don’t miss out — simply click here now to claim your copy today.

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Source: FULL ARTICLE at DailyFinance

Merck Props the Dow Up

By Dan Dzombak, The Motley Fool

US Quits: Total Nonfarm Chart

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The Dow Jones Industrial Average is down slightly after finishing higher for the past six trading sessions. As of 1:15 p.m. EDT the Dow is down nine points, or 0.06%, to 14,436. The S&P 500 is down 0.26% to 1,552.

There were two economic releases this morning.

Report

Period

Result

Previous

NFIB Small Business Economic Trends

February

90.8

88.9

Job openings

January

3.69 million

3.61 million

The one to pay attention to is the Department of Labor’s job openings report, which showed that job openings edged up in January by 80,000. Hiring and turnover were unchanged from December at respective rates of 3.1% and 3%. The jobs market is a key factor for the U.S. economy, and it has been holding back the domestic recovery as the unemployment rate stays high. Rising job openings show a healthier economy as companies look for more employees.

US Job Openings: Total Nonfarm data by YCharts.

The report also showed 2.2 million quits — the highest level since 2008. The level of quits is seen as a barometer for employees’ confidence in their ability to find another job and, thus, their confidence in the economy. The level of quits has risen rather steadily since 2009.

US Quits: Total Nonfarm data by YCharts.

Today’s Dow leader
Today’s Dow leader is Merck , up 3.3%. Earlier today, a medical advisory panel said a large trial for Vytorin can continue. Vytorin is a cholesterol-limiting drug that, along with Zetia, provided the first real competition for Pfizer‘s Lipitor. The trial includes 18,000 participants, was started in 2005, and is scheduled to end in September 2014.

Merck is trying to show conclusively that Vytorin is significantly more effective than Zocor, another Merck drug that is now available in generic form. Vytorin currently has sales of about $1.75 billion per year, down from 2008, when two smaller studies raised doubts over Vytorin. The first study showed that Vytorin led to an increased risk of cancer, while the second study showed that Vytorin was no more effective than generic Zocor. The continuation of the study is good news for Merck, as it shows that the panel believes the study has a good chance at a positive result. A successful Vytorin trial would be a boon for Merck going forward, but we won’t know the result until next September.

Can Merck beat the patent cliff?
This titan of the pharmaceutical industry stumbled into 2013 and continues to battle patent expirations and pipeline problems. Is Merck still a solid dividend play, or should investors be looking elsewhere? In a new premium research report on Merck, the Fool tackles all of the company’s moving parts, its major market opportunities, and reasons both to buy and to sell. To find out more, click here to claim your copy today.

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Source: FULL ARTICLE at DailyFinance

Heart Problems and Downgrades Cause Dow Stocks to Fall

By Matt Thalman, The Motley Fool

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After a seven-day winning streak for the Dow Jones Industrial Average , today may be the day when investors begin to take profits. As of 12:55 p.m. EDT, the blue-chip index is up less than a point, having traded within a tight range all day. There are more losers than winners on the Dow, but a big gain by Merck is helping to keep the index afloat.

It’s important for long-term individual investors to remember that day-traders, money managers, and other Wall Street types will begin taking profits now that the markets have run so high so quickly. If the Dow falls in the short term, don’t panic or follow the herd off the cliff.

The S&P 500 is down 0.23%, while the NASDAQ has lost 0.4%.

Today’s Dow laggards
The Dow’s big pharmaceutical stocks are heading in opposite directions today. Shares of Merck rose by 3.3% after an independent monitoring board gave the company’s cholesterol drug Vytorin a pass, allowing its drug trial to continue. This drug could be a blockbuster for Merck, similar to Pfizer‘s Lipitor.

Speaking of which, Pfizer is seeing much less success today, with shares down 0.8%. Shares began falling this morning after the U.S. Food and Drug Administration released a warning that Pfizer’s antibiotic Zithromax can cause a life-threating irregular heartbeat. A research study performed by The New England Journal of Medicine back in May concluded that Pfizer’s drug carried a higher risk of cardiovascular death than various other antibacterial drugs.

Shares of Cisco are lower by 1.3% today after Standpoint Research downgraded the stock this morning from a buy to a hold. Cisco did recently hit a new 52-week high at $21.98, which may have prompted Standpoint’s analysts to change their rating.

Another Dow stock moving lower after a recent downgrade is General Electric . Yesterday, Shannon O’Callaghan from Nomura Securities downgraded the stock from buy to neutral, although he kept his price target at $24 per share. General Electric‘s stock is currently down 1%.

For GE, the financial crisis struck a blow, but management took advantage of the market‘s dip to make strategic bets in energy. If you’re a GE investor, you need to understand how these bets could drive this company to become the world’s infrastructure leader. At the same time, you need to be aware of the threats to GE‘s portfolio. To help, we’re offering comprehensive coverage for investors in a premium report on General Electric, in which our industrials analyst breaks down GE‘s multiple businesses. You’ll find reasons to buy or sell GE today. To get started, click here now.

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Source: FULL ARTICLE at DailyFinance