Tag Archives: Matt Posard

Illumina and Kindstar Global Announce Strategic Collaboration to Facilitate Clinical Adoption of Ill

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Illumina and Kindstar Global Announce Strategic Collaboration to Facilitate Clinical Adoption of Illumina Technologies in Asia

SAN DIEGO & WUHAN, China–(BUSINESS WIRE)– Illumina, Inc. (NAS: ILMN) and Kindstar Global (Kindstar) today announced they are entering into a strategic collaboration whereby Kindstar will validate and implement molecular assays in their laboratories, leveraging Illumina’s TruSightTM content sets, Infinium® Dx CytoSNP-12 assay and NuPCRTM reagents. The collaboration will enable Kindstar to expand its esoteric and specialty testing services offerings within its network of more than 3,300 hospitals across China.

“Kindstar’s adoption of Illumina’s TruSight technology across its extensive network in China speaks to the breadth and depth of content in this innovative portfolio,” said Matt Posard, Senior Vice President and General Manager of Illumina’s Translational and Consumer Genomics business. “Next-generation sequencing is enabling a dramatic improvement in both coverage and accuracy for molecular diagnostics, and we look forward to additional partnerships that continue to drive this improvement forward.”

“Kindstar is excited to offer services in China based on Illumina’s products including the TruSight content sets,” said Dr. Shiang Huang, Founder and CEO of Kindstar. “Leveraging Illumina‘s technology will enable us to offer the highest quality and most specialized diagnostics.”

About Illumina

Illumina (www.illumina.com) is a leading developer, manufacturer, and marketer of life science tools and integrated systems for the analysis of genetic variation and function. We provide innovative sequencing and array-based solutions for genotyping, copy number variation analysis, methylation studies, gene expression profiling, and low-multiplex analysis of DNA, RNA, and protein. We also provide tools and services that are fueling advances in consumer genomics and diagnostics. Our technology and products accelerate genetic analysis research and its application, paving the way for molecular medicine and ultimately transforming healthcare.

About Kindstar Global

Kindstar Global, with laboratory facilities in Beijing, Shanghai and Wuhan, provides esoteric diagnostic testing services to hospitals and physicians in every province of China. Kindstar is the first and largest esoteric diagnostic testing business in China, providing laboratory testing services to over 3,300 Chinese hospitals, including 930 tertiary hospitals (classification for largest leading hospitals). Kindstar is becoming the partner of choice to physicians in China for advanced diagnostics in many medical specialties including hematology, oncology, infectious diseases and medical genetics.

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From: http://www.dailyfinance.com/2013/04/18/illumina-and-kindstar-global-announce-strategic-co/

Illumina Launches TruSight™ Tumor Content Set

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Illumina Launches TruSight™ Tumor Content Set

Enables Somatic Variant Detection in Solid Tumors Using Next-Generation Sequencing (NGS)

SAN DIEGO–(BUSINESS WIRE)– Illumina, Inc. (NAS: ILMN) today announced the next product in its TruSight line of content sets, TruSight Tumor, for NGS-based somatic variant detection in solid tumors. TruSight Tumor provides optimized amplicon-based library preparation of 26 oncogenes and tumor suppressor genes selected for their involvement in common solid tumors, including lung, colon, melanoma, gastric, and ovarian cancer.

TruSight Tumor also offers a comprehensive NGS-based tumor profiling solution that provides a broader and more cost-effective view of tumor heterogeneity compared to genotyping-based methods. Researchers can simultaneously detect somatic changes in multiple genes across the tumor genome, as referenced in industry guidelines, as well as emerging biomarkers implicated in pharmaceutical clinical trials. Designed for use with formalin-fixed paraffin-embedded (FFPE) samples, TruSight Tumor enables high levels of sensitivity for minor allele detection (below 5%), with limited DNA input requirements.

“TruSight Tumor is designed to run on Illumina’s industry-leading sequencing platforms and enables clinical researchers to understand the molecular heterogeneity of FFPE tumor samples,” said Matt Posard, Senior Vice President and General Manager of Illumina’s Translational and Consumer Genomics business. “This technology has the potential to expand candidates for targeted therapies who may otherwise be missed with single variant or single gene approaches.”

“Tumor characterization using next-generation sequencing enables clinical research laboratories to gain a deeper understanding of underlying biology. In order to detect clinically relevant variants, it is important to look beyond single genes or hotspot mutations while achieving very low levels of sensitivity,” said Dr. Robert Daber, Technical Director of Clinical Genomics, Center for Personalized Diagnostics, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania.

TruSight Tumor is the first content set designed for somatic variant detection on the Illumina MiSeq® platform. As a portfolio, TruSight content sets are designed for high performance targeted sequencing to meet the specific needs of the clinical research laboratory by providing high analytical sensitivity and specificity. They offer exceptional performance in the capture and sequencing of targeted genomic regions, and are selected through collaborations with experts from leading institutions.

TruSight content sets are for research use only and not intended for diagnostic use. TruSight Tumor is now available for order with shipment expected in Q2’13. For more information, visit www.illumina.com/TruSightTumor.

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Source: FULL ARTICLE at DailyFinance