Tag Archives: DNA

Fly study finds two new drivers of RNA editing

RNA editing gives organisms a way to adapt the instructions that their DNA provides for making proteins. Few people would have described RNA editing as a simple process, but a new paper in Nature Communications demonstrates the process as more complex and difficult to predict than previously assumed. The study, done in living fruit flies, discovered two new mechanisms that govern editing in a key neurodevelopmental gene. …read more

Source: FULL ARTICLE at Phys.org

Woolly mammoth DNA may lead to a resurrection of the ancient beast

By hnn

The pioneering scientist who created Dolly the sheep has outlined how cells plucked from frozen woolly mammoth carcasses might one day help resurrect the ancient beasts.

The notional procedure – bringing with it echoes of the Jurassic Park films – was spelled out by Sir Ian Wilmut, the Edinburgh-based stem-cell scientist, whose team unveiled Dolly as the world’s first cloned mammal in 1996.

Though it is unlikely that a mammoth could be cloned in the same way as Dolly, more modern techniques that convert tissue cells into stem cells could potentially achieve the feat, Wilmut says in an article today for the academic journalism website, The Conversation.

“I’ve always been very sceptical about the whole idea, but it dawned on me that if you could clear the first hurdle of getting viable cells from mammoths, you might be able to do something useful and interesting,” Wilmut told the Guardian….

Source:
Guardian (UK)

Source URL:
http://www.theguardian.com/science/2013/jul/31/woolly-mammoth-dna-cloning

Date:
7-31-13

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Source: FULL ARTICLE at History News Network – George Mason University

Field study shows tigers in India follow corridors between groups to maintain gene flow

(Phys.org) —A team of researchers working in India has found that tigers living in separate geographic areas mate with tigers from other groups by traversing natural corridors. In their paper published in Proceedings of the Royal Society B, the team explains how they analyzed tiger DNA samples from different groups to learn more about their mating patterns. …read more

Source: FULL ARTICLE at Phys.org

Happily Ever After: How Stories Can Make You Healthier – and More Successful

By Erika Andersen, Contributor If you’ve been following this blog or have read any of my books, you know that I’m a huge fan of stories and story-telling. Telling stories has been essential to our evolution as human beings. Especially in the times before most people could read or write – which means for about the first 95% of human history – stories were the most memorable and easily replicable way to transmit important information. We used them to communicate values and taboos, fears and hopes, our sense of ourselves and our history.  I think of stories as the DNA of pre-literate society: if you want to know what a people considered essential in their culture, look to their stories. …read more

Source: FULL ARTICLE at Forbes Latest

'Cowcatcher' enzyme fixes single-strand DNA

Every time one of your cells divides, it exposes its most essential component to great danger: its genome, the sum total of all its genetic information, embodied in the double-stranded helix of DNA. Prior to cell division, this DNA splits into two single strands, each bearing sequences of biochemical bases that form templates for the genomes of the daughter cells. These single strands are particularly vulnerable to assaults by reactive oxygen species—toxic byproducts of respiration—that could cause changes in the genetic information they contain. …read more

Source: FULL ARTICLE at Phys.org

Find helps scientists map waves of migration across the continents

The discovery of an “early modern human” dating from 40,000 years ago in a cave outside Beijing, and a comparison of the individual’s DNA with that of populations around the globe, are providing new pieces in the puzzle of how Homo sapiens left their African origins to expand across the continents. …read more

Source: FULL ARTICLE at Phys.org

Stiffening the backbone of DNA nanofibers

An international collaboration including researchers from the NIST Center for Nanoscale Science and Technology and the Universidad San Francisco de Quito, Ecuador have fabricated a self-assembled nanofiber from a DNA building block that contains both duplex (two-stranded) and quadruplex (four-stranded) DNA. This work is a first step toward the creation of new structurally heterogeneous (quadruplex/duplex), yet controllable, DNA-based materials exhibiting novel properties suitable for bottom-to-top self-assembly for nanofabrication, including self-organization of both inorganic materials (nanoparticles) and molecular electronics components. …read more

Source: FULL ARTICLE at Phys.org

Designated with Walker back, Inge draws praise

By Tom Singer Baseball players with a winner’s DNA are often credited with “doing those little things that do not show up in the box score.” Brandon Inge’s entire Pittsburgh stay was like that. The veteran infielder was designated for assignment on Tuesday — creating s roster spot for Neil Walker’s return from the disabled list — but his influence was far more pronounced than his stat line. …read more

Source: FULL ARTICLE at MLB

Adam & Albert May Rewrite the History of Man

By hnn

The DNA of Albert Perry may change the story of human origins. Perry, an African-American, approached a DNA testing company to find out more about his ancestry. The results would have come as quite a surprise (had he lived to see them), and have raised questions for geneticists around the world.

It turns out that Perry carried a very different type of Y chromosome, never seen before. Every male has a Y chromosome, which is a piece of DNA inherited by sons from their fathers. But, unlike most DNA, the Y chromosome is not shuffled as it is passed down, and changes only slowly through mutation. Tracking these mutations allows scientists to create a genetic tree of fathers and sons going back through time.

As a man may have several sons or none, some branches of the genetic tree die out each generation, while others become more common. Going back through time it is therefore inevitable that all modern Y chromosomes must descend from from one man at some point in the past. He has become known as “Y-chromosomal Adam”….

Source:
RealClearScience

Source URL:
http://www.realclearscience.com/articles/2013/07/23/adam__albert_may_rewrite_the_history_of_man_106605.html

Date:
7-23-13

…read more

Source: FULL ARTICLE at History News Network – George Mason University

Researchers use DNA origami technique to build nanoantennas with docking sites

A team of researchers working at Germany’s Technische Universität Braunschweig has succeeded in using a previously known DNA origami construction technique to build a nanoantenna with a docking site. First published in the journal Science, the paper written by the team has now been made publicly available for open access. …read more

Source: FULL ARTICLE at Phys.org

Frank Lee Smith’s Family Settles Lawsuit With Broward Sheriff’s Office Over DNA Exoneration

By The Huffington Post News Editors

Frank Lee Smith died of cancer on death row, just months before DNA exonerated him of raping and murdering an 8-year-old girl in Fort Lauderdale. Now, more than 13 years later, his family’s civil lawsuit against the Broward Sheriff’s Office and two detectives accused of framing him has finally been settled.

Smith’s death made him a national symbol because it was the first case in the U.S. that scientifically proved an innocent man had died in prison for a crime he didn’t commit.

But the financial settlement reached with the Sheriff’s Office — on behalf of the agency and retired detectives Richard Scheff and Philip Amabile — is much less than the millions awarded in Broward’s other notorious wrongful conviction cases.

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More on Miami Crime

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Source: FULL ARTICLE at Huffington Post

Gut microbes influence host species evolution

There was a time when we thought the sum of the all the cells in our body, as mapped in our DNA, is what defines our living, breathing bodies. Then we discovered that inside us, mostly in our guts, live huge colonies of microbes, that are essential partners in keeping us alive and well. The mutually beneficial partnership is known as symbiosis… …read more

Source: FULL ARTICLE at Medical News Today

DNA Clinches It: Confessed Boston Strangler Killed Woman

It’s official. DNA tests confirm that the man who once claimed to be the Boston Strangler did indeed kill the woman believed to be the serial killer’s last victim, authorities said today. (They were nearly certain last week, but today’s results provide the final confirmation.) Albert DeSalvo admitted to… …read more

Source: FULL ARTICLE at Newser – Home

DNA links Boston Strangler suspect to last victim

DNA tests confirm that the man who once claimed to be the Boston Strangler did in fact kill the woman believed to be his last victim and was likely responsible for the deaths of the other victims, authorities said.

Albert DeSalvo admitted to killing Mary Sullivan and 10 other female victims in the Boston area between 1962 and 1964, but he later recanted his story.

The DNA finding “leaves no doubt that Albert DeSalvo was responsible for the brutal murder of Mary Sullivan” and it was “most likely” that he also was the Boston Strangler, Massachusetts Attorney General Martha Coakley said.

Boston investigators unearthed DeSalvo’s remains last week so they could test DNA from the scene of Sullivan’s death and get a match with DeSalvo, that excluded 99.9 percent of suspects.

Mary Sullivan was 19 years old in 1964 when she was brutally raped and killed in her Boston bedroom. The only link to her killer was DeSalvo’s confession, which was subject of scrutiny since there was never any concrete evidence collected at the scene.

Advances in DNA testing have provided authorities with a “familial match” from evidence collected from the crime scene and DeSalvo.

Boston police located a water bottle used by a nephew of DeSalvo and found a match in the Y chromosome, which eliminates 99.9 percent of the population to the crime. Sullivan is the only victim for which DNA evidence is available.

Authorities in the 1960s had the foresight to set aside evidence extracted from Sullivan’s body and a blanket and placed it in a laboratory until science could be employed to link a suspect.

After a few earlier attempts, the DNA evidence was submitted to two independent labs last fall and a profile was developed. The evidence in the case has never changed, only the technology for law enforcement to explore it.

An attorney for DeSalvo’s family has said even a perfect match wouldn’t determine he killed Sullivan.

DeSalvo, married with children, a blue-collar worker and Army veteran, confessed to the 11 Boston Strangler murders, as well as two others.

Represented by F. Lee Bailey, DeSalvo was never convicted of the Boston Strangler killings. Rather, he was sentenced to life in prison for a series of armed robberies and sexual assaults and was stabbed to death in the state’s maximum security prison in Walpole in 1973 — but not before he recanted his confession.

Officials stressed that the DNA evidence links DeSalvo only to Sullivan’s killing and that no DNA evidence is believed to exist for the other Boston Strangler slayings.

State Attorney General Martha Coakley, however, said investigators hoped that solving Sullivan’s case might put to rest doubts about DeSalvo’s guilt.

Though the murders were attributed to DeSalvo after he confessed, investigators believed the murders were committed by more than one person.

The infamous Boston Strangler stalked the city in the early 1960s, killing a total of 13 women over two years, the report said. The victims were all single women between the ages of 19 to 85. All were sexually assaulted, then strangled in their …read more

Source: FULL ARTICLE at Fox US News

A tighter fit with artificial DNA

An artificial base that enhances the protein-binding affinity and selectivity of DNA expands the DNA machinery.DNA aptamers are expected to play an important role in the diagnosis and treatment of various cancers and other gene-related diseases. These nucleic acids, which bind target substances such as proteins and cells, are typically generated through in vitro evolution methods. Ichiro Hirao and colleagues from the RIKEN Center for Life Science Technologies have now developed a new generation strategy based on an expanded genetic alphabet that improves the affinity and selectivity of DNA aptamers1. …read more

Source: FULL ARTICLE at Phys.org

Land Rover Green Lights Evoque Convertible for Production, Report Says

By Jens Meiners

Land Rover has given the green light to a convertible version of the Range Rover Evoque, according to an article by British publication What Car?. The piece quotes an unnamed source at Land Rover as saying, “The Evoque convertible now has the green light, it’s going to be built.” The publication goes on to say that production will begin next year. We were unable to corroborate this information through our channels, and a Jaguar Land Rover spokesman declined to confirm the rumor.

The Evoque convertible was shown in concept form at the Geneva auto show in 2012, and drew mostly positive reviews from observers. “There was a lot of excitement around the concept when it was shown in the U.S.,” Land Rover tells us. The design community, however, was more ambiguous, as the softtop version lacks the aggressively styled roofline that is such an important part of the Evoque’s styling DNA.



If it’s built, the Evoque convertible will join the three-door coupe and a five-door version, the latter of which currently generates roughly 80 percent of the vehicle’s sales volume. As an open-top crossover, the Evoque cabriolet would have just one direct competitor: the Nissan Murano CrossCabriolet.

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Source: FULL ARTICLE at Car & Driver

ObamaCare and Regulatory Lock-In Threatens The Biggest Healthcare Tech Revolution in History

By Mark P. Mills, Contributor

We are entering an era of big government medicine.  Few could claim that ObamaCare hews to the market principles of Adam Smith, or state’s rights, or individual choice.  And Silicon Valley’s DNA of unbridled innovation?  Not so much. …read more

Source: FULL ARTICLE at Forbes Latest

The Conjuring to Scare Up a Sequel

The Conjuring won’t hit theaters until July 19, but New Line is already lining up a sequel to James Wan’s horror pic.

Set in 1971 Rhode Island, The Conjuring is inspired by the work of real-life paranormal investigators Ed and Lorraine Warren, played by Patrick Wilson and Vera Farmiga, respectively. Ron Livingston and Lili Taylor portray a father and mother of young daughters who were plagued by a haunted house.

“Horror is very much a part of the DNA of New Line — Nightmare on Elm Street, Friday the 13th, The Rite, and the Final Destination films,” said New Line president Toby Emmerich. “This is as good a horror movie as we’ve ever made… We think it will have great playability.”

Continue reading…

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Source: FULL ARTICLE at IGN Movies

British lawmakers blast slow horsemeat scandal probe

British lawmakers on Tuesday condemned the slow pace of the investigation into Europe’s horsemeat scandal, with no prosecutions in Britain six months after the problems emerged.

Parliament’s Environment, Food and Rural Affairs Committee said British and Irish authorities had failed to recognise the scale of the scandal, which led to thousands of beef products being pulled from supermarkets across Europe after they were found to contain horsemeat.

“We are concerned at the failure of authorities in both the UK and Ireland to acknowledge the extent of this and to bring prosecutions,” the committee said in a report.

It added that the scandal had revealed that a “complex, highly organised network” of companies were involved in the “fraudulent and illegal” mislabelling of meat.

“We are dismayed at the slow pace of investigations and would like assurance that prosecutions will be mounted where there is evidence of fraud or other illegal activity,” the report added.

The lawmakers acknowledged that horsemeat was found in a “relatively small” number of beef products, with only 4.66 percent of products tested across the EU found to contain more than one percent of horse DNA.

The scandal started in January, when beefburgers sold in several British and Irish supermarket chains were found to contain horsemeat, before spreading to more than a dozen other countries.

A spokesman for the Environment, Food and Rural Affairs ministry said it had set up an independent review into how the problem was able to go undetected.

“The police are investigating how products containing horsemeat came to be on sale in the UK and they will take action where any unlawful activity has taken place,” the spokesman added.

…read more

Source: FULL ARTICLE at Fox World News