Tag Archives: Grand Challenges

An Investment Opportunity for a Healthy World

By Dan Newman, The Motley Fool

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Since 1981, 25 million people have died from HIV/AIDS. An estimated 1.7 million died in 2011 due to AIDS-related causes, with another 2.5 million newly infected with HIV. Beyond the human cost, the U.S. government spent $28 billion fighting HIV in 2012, and some African countries lose 1% in GDP growth each year due to the disease. It’s difficult to grasp these numbers, but it’s a problem crying out for several solutions.

One such solution is offered by Female Health Company : FC2, the only female condom approved by the Food and Drug Administration and the World Health Organization.

Social opportunity
The Bill and Melinda Gates Foundation recently called for proposals for its Grand Challenges in Global Health grant program. One of the topics addressed this year is “reinventing the condom.” As the blog post describes the issue:

It may seem obvious, but the success and impact of any public health tool hinges on that tool being used consistently and correctly by those who need it. Vaccines sitting on shelves don’t prevent disease. New tuberculosis drug regimens won’t help if patients stop taking them halfway through the necessary days. Likewise, the potential value of condoms is limited by inconsistent use.

The FC2 condom is a superb public health tool that allows women to initiate protection against sexually transmitted diseases. As to making sure it is used consistently and correctly, Female Health has a variety of initiatives. In South Africa, Female Health has distributed 20 million condoms and trained 10,000 health providers. The company also runs a website with product information and training, it will be investing $14 million over the next six years in HIV/AIDS and reproductive education with global agencies, and it has set a goal of reaching 120 million more women in the poorest countries by 2020.

Profitable opportunity
Some may guess that doing business with developing countries wouldn’t allow for a very profitable business. However, when South African companies like Sasol  — which estimated 18% of its workforce carried HIV in 2007 — must dedicate departmental budgets to HIV/AIDS, there are plenty of opportunities for Female Health to cover costs and earn a return. A healthier workforce for Sasol would simply cost less for the company, and Female Health can help companies like Sasol achieve a healthier workforce.

Closer to home, at least 3% of Washington, D.C., residents carry HIV/AIDS. Working with Johns Hopkins, a study found:

…a public-private partnership to provide and promote FC2 female condoms, prevented enough HIV infections in the first year alone to save over $8 million in avoided future medical care costs (over and above the cost of approximately $445,000 for the program). This means that for every dollar spent on the program, there was a cost savings of nearly $20.

FHCO Revenue TTM data by YCharts.

Risky opportunity
Female Health‘s major customers are from the public sector — like the United Nations Population Fund and USAID — which the company warns can make for lumpy revenue due to

From: http://www.dailyfinance.com/2013/04/18/an-investment-opportunity-for-a-healthy-world/

BRAIN Initiative Challenges Researchers to Unlock Mysteries of Human Mind

By Francis Collins and Arati Prabhakar

Note: Have questions about the BRAIN Initiative? Today, at 12:00 p.m. EDT, Tom Kalil, Innovation Advisor; Dr. Francis Collins, Director of National Institutes of Health; and Dr. Arati Prabhakar, Director of the Defense Advanced Research Projects Agency (DARPA) will answer your questions. Ask on Twitter with #WHChat.

Today at the White House, President Obama unveiled the “BRAIN” Initiative—a bold new research effort to revolutionize our understanding of the human mind and uncover new ways to treat, prevent, and cure brain disorders like Alzheimer’s, schizophrenia, autism, epilepsy, and traumatic brain injury.

The BRAIN Initiative — short for Brain Research through Advancing Innovative Neurotechnologies — builds on the President’s State of the Union call for historic investments in research and development to fuel the innovation, job creation, and economic growth that together create a thriving middle class.

The Initiative promises to accelerate the invention of new technologies that will help researchers produce real-time pictures of complex neural circuits and visualize the rapid-fire interactions of cells that occur at the speed of thought. Such cutting-edge capabilities, applied to both simple and complex systems, will open new doors to understanding how brain function is linked to human behavior and learning, and the mechanisms of brain disease.

In his remarks this morning, the President highlighted the BRAIN Initiative as one of the Administration’s “Grand Challenges” – ambitious but achievable goals that require advances in science and technology to accomplish. The President called on companies, research universities, foundations, and philanthropies to join with him in identifying and pursuing additional Grand Challenges of the 21st century—challenges that can create the jobs and industries of the future while improving lives.

In addition to fueling invaluable advances that improve lives, the pursuit of Grand Challenges can create the jobs and industries of the future.

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Source: FULL ARTICLE at The White House

Fact Sheet: BRAIN Initiative

By The White House

If we want to make the best products, we also have to invest in the best ideas… Every dollar we invested to map the human genome returned $140 to our economy… Today, our scientists are mapping the human brain to unlock the answers to Alzheimer’s… Now is not the time to gut these job-creating investments in science and innovation. Now is the time to reach a level of research and development not seen since the height of the Space Race.”

President Barack Obama, 2013 State of the Union

In his State of the Union address, the President laid out his vision for creating jobs and building a growing, thriving middle class by making a historic investment in research and development.

Today, at a White House event, the President unveiled a bold new research initiative designed to revolutionize our understanding of the human brain. Launched with approximately $100 million in the President’s Fiscal Year 2014 Budget, the BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Initiative ultimately aims to help researchers find new ways to treat, cure, and even prevent brain disorders, such as Alzheimer’s disease, epilepsy, and traumatic brain injury.

The BRAIN Initiative will accelerate the development and application of new technologies that will enable researchers to produce dynamic pictures of the brain that show how individual brain cells and complex neural circuits interact at the speed of thought. These technologies will open new doors to explore how the brain records, processes, uses, stores, and retrieves vast quantities of information, and shed light on the complex links between brain function and behavior.

This initiative is one of the Administration’s “Grand Challenges” – ambitious but achievable goals that require advances in science and technology. In his remarks today, the President called on companies, research universities, foundations, and philanthropists to join with him in identifying and pursuing the Grand Challenges of the 21st century.

The BRAIN Initiative includes:

  • Key investments to jumpstart the effort: The National Institutes of Health, the Defense Advanced Research Projects Agency, and the National Science Foundation will support approximately $100 million in research beginning in FY 2014.

  • Strong academic leadership: The National Institutes of Health will establish a high-level working group co-chaired by Dr. Cornelia “Cori” Bargmann (The Rockefeller University) and Dr. William Newsome (Stanford University) to define detailed scientific goals for the NIH’s investment, and to develop a multi-year scientific plan for achieving these goals, including timetables, milestones, and cost estimates.

  • Public-private partnerships: Federal research agencies will partner with companies, foundations, and private research institutions that are also investing in relevant neuroscience research, such as the Allen Institute, the Howard Hughes Medical Institute, the Kavli Foundation, and the Salk Institute for Biological Studies.

  • Maintaining our highest ethical standards: Pioneering research often has the potential to raise new ethical challenges. To ensure this new effort proceeds in ways that continue to adhere to our highest standards of research protections, the President will direct his Commission for the Study of Bioethical Issues to explore the ethical, legal, and societal implications raised by this research …read more
    Source: White House Press Office